Presentation Details
Evaluating Emotional And Cognitive Domains In Dogs With And Without Chronic Pain

Morgan Ferrans1, 5, Maggie Creamer1, 5, Liubov Arbeeva2, Masataka Enomoto5, Kara Moore1, Sina Mahs1, Vanessa Woods4, Shelby Carter4, Kyle Smith1, Francis Keefe3, Brian Hare4, Benedict D.X.Lascelles5, 6, Margaret Gruen1, 6.

1Comparative Behavioral Research and Thinking Pets Program, Raleigh, NC, USA.2Thurston Arthritis Research Center, Chapel Hill, NC, USA.3Duke University School of Medicine, Durham, NC, USA.4Duke University, Durham, NC, USA.5Translational Research in Pain, Raleigh, NC, USA.6Comparative Pain Research and Education Center, Raleigh, NC, USA

Abstract


Although chronic pain in humans is known to affect cognition and emotion, biopsychosocial impacts of pain in other species are poorly understood. To better characterize canine chronic pain, we developed a battery of cognitive and emotional domain tests and compared dogs with and without osteoarthritis (OA). Subjects (n=48) will complete the behavioral battery twice, four weeks apart. We present preliminary analyses (n=17) examining group differences and consistency of performance (test-retest reliability) across visits. At the first timepoint, we observed differences (Welch’s independent sample t-tests) between groups in some emotional and cognitive measures, but not always in the expected direction. Test-retest consistency (intraclass correlation) was good in several novel emotional outcome measures as well as cognitive measures, suggesting stable individual performance over time. We also evaluated potential systematic bias between sessions using paired t-tests. In future work, we will increase sample size and number of timepoints, and include an OA-pain group receiving effective analgesia to test whether reducing pain alters cognition and emotion.

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