Presentation Details
| X Marks the Spot: Mapping the Neural Correlates of Spatial Navigation Behavior in Clonal Fish Emma Yamamoto, Siobhan Calhoun, Abigail Trocinski, Amelia Engelsgjerd, Kate Laskowski. University of California, Davis, Davis, CA, USA |
Abstract
Exposure to stressors such as predation risk during early life can affect long term behavioral phenotypes, including the ability to navigate through space. The long-term effects of stress on later behavioral decisions suggests important organizational changes in the brain, but we are still uncovering exactly which mechanisms underlie these changes. Here, we investigate the effects of developmental stress on spatial navigation using a naturally clonal fish species, which offers the unique ability to isolate environmental effects from genetics when examining differences in behavior and neural activation. Preliminary data suggests that, when tested as adults, individuals reared with predator cues were more successful at navigating a one turn maze than individuals reared under control conditions, suggesting long-term effects of this stressor. We utilized a pS6 immunohistochemical protocol to analyze how rearing treatment impacts levels of neural activity in brain regions related to sensory processing and navigation. Our results show early life predation stress can have long lasting impacts on navigation, and these differences are reflected in neural processing.
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No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the author.
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